Profesora Asociada
Universidad de Chile
Programa Genética Humana, ICBM
Facultad de Medicina.
Universidad de Chile
Líneas de Investigación
Marcadores genéticos asociados a depresión mayor en la población Chilena. Predictores genéticos de la respuesta farmacológica
Publicaciones
Ventura-Juncá, Raúl, A Symon, P López J, Fiedler, G Rojas C, Heskia P, Lara, F Marín, V Guajardo, AV Araya, J Sasso, L Herrera. 2014. Relationship of cortisol levels and genetic polymorphisms to antidepressant response to placebo and fluoxetine in patients with major depressive disorder: a prospective study. BMC Psychiatry Aug 3;14:220. doi: 10.1186/s12888-014-0220-0 ISI 2.24 ISSN 1471-244X
Romero, P, V Fernández, M Slabaugh, N Seleme, N Reyes, P Gallardo, L Herrera, L Peña, P Pezo, M Moraga. 2014. Pan-American Mitochondrial DNA haplotypes in Chilean patients with Leber’s Hereditary Optic Neuropathy. Molecular Vision ISI : 2.607 ISSN 1090-0535
Quiñones L, Lavanderos M, Cayun J, García-Martin E, Agúndez J, Caceres D, Roco A, Morales J,Herrera L, Encina G, Isaza C, Redal M, Larovere L, Soria N, Eslava-Schmalbach J, Castaneda-Hernandez G, Lopez-Cortes A, Magno L, Lopez M, Chiurillo M, Rodeiro I, Castro de Guerra D, Teran E, Carrizo E, Lares-Assef. 2014. Perception of the Usefulness of Drug/Gene Pairs and Barriers for Pharmacogenomics in Latin America Curr Drug Metab. 2014 Feb 2. ISI 3.487 ISSN 1875-5453
Ventura-Juncá, R, Herrera, L. 2012. Epigenetic alterations related to early-life stressful events. Acta Neuropsychiatrica 24: 255- 265 ISI 0.577 ISSN 1601-521
Fernández-Guasti A, Fiedler J, Herrera L, and Handa JR. 2012 Sex, Stress and Mood disorders: At the intersection of Adrenal and Gonadal Hormones. Horm Metab Res; 44:1–12 ISI 2.188 ISSN 0018-5043
Romero P, Sanhueza F, Lopez P, and Herrera L. 2011. c.194 A>C (Q65P) mutation in the LMX1B gene in patients with Nail Patella syndrome associated with glaucoma. Mol Vis 17:1929-1939. ISI 2.607 ISSN 2222-3959
González S, Aguilera S, Alliende C, Urzúa U, G Quest AF, Herrera L,
Molina C, Hermoso M, Ewert P, Brito M, Romo R, Leyton C, Pérez P, González MJ. 2011. Alterations in type I-hemidesmosome components suggest epigenetic control in salivary glands from Sjögren’s Syndrome patients. Arthritis Rheum. 63:1106-15. ISI 8.136 ISSN 2326-5205
Romero P, Moraga M. Herrera L. 2010. Different phenotypes of Lattice Corneal Dystrophy type I in patients with 417C>T (R124C) and 1762A>G (H572R) mutations in the TGFBI (BIGH3) gene. Mol Vis 16:1601-1609. ISI 2.607 ISSN 2222-3959
Romero P, Vogel M, Díaz J, Romero M, Herrera L. 2008. Anticipation in familial lattice corneal dystrophy type I with R124C mutation in the TGFBI (BIGH3) gene. Mol Vis 14: 829 – 835. ISI 2.607 ISSN 2222-3959
Pérez-Pastene C, Graumann R, Diaz-Grez F, Miranda M, Venegas P, Godoy OT, Layson L, Villagra R, Matamala JM, Herrera L, Segura-Aguilar J. 2007. Association of GST M1 null polymorphism with Parkinson’s disease in a Chilean population with a strong Amerindian genetic component. Neurosci Lett. 418:181-185. ISI 2.114 ISSN 0304-3940
Araya AV, Rojas P, Fritsch R, Rojas R, Herrera L, Rojas G, Gatica H, Silva H, Fiedler JL 2006. Early response to venlafaxine antidepressant correlates with lower ACTH levels prior to pharmacological treatment. Endocrine 30:289-98. ISI 2.090 ISSN 1559-0100
Bravo JA, Parra CS, Arancibia S, Andres S, Morales P, Herrera-Marschitz M, Herrera L, Lara HE, Fiedler JL. 2006. Adrenalectomy promotes a permanent decrease of plasma corticoid levels and a transient increase of apoptosis and the expression of Transforming Growth Factor beta1 (TGF-beta1) in hippocampus: effect of a TGF-beta1 oligo-antisense. BMC Neurosci 7:40 ISI 4.041 ISSN 1471-2202
Figueroa C, Peralta A, Herrera L, Castro P, Gutiérrez A, Valenzuela J, Aguillon JC, Quera R, Hermoso MA. 2006. NOD2/CARD15 and Toll-like 4 receptor gene polymorphism in Chilean patients with inflammatory bowel disease. Eur Cytokine Netw. 17:125-130. ISI 2.12 ISSN 1148-5493
Herrera L, Ottolenghi C, Garcia-Ortiz JE, Pellegrini M, Manini F, Ko MS, Nagaraja R, Forabosco A, Schlessinger D. 2005. Mouse ovary developmental RNA and protein markers from gene expression profiling. Dev Biol. 279: 271- 290. ISI 4.689 ISSN 0012-1606
Capítulos de Libro
Herrera L. 2014. «Regulación de la expresión génica» pags 113-131. En “Genética Humana”. M Berríos Ed. Editorial Mediterráneo. 286 pág. ISBN 9789562203647
Barrios, A. y Herrera L. 2012 Mecanismos Epigenéticos Involucrados en el Desarrollo de la Epilepsia. Revista Chilena de Epilepsia 1: 5-15. ISSN 0719-5397
Herrera, L., Pinto, M y Moraga M. 2006. Enciclopedia Temática Escolar “Cuerpo Humano y Genética. Copesa Editorial SA, 2006. 94 páginas